Author: Clark Weddell

The articles listed here represent a broad spectrum of topics – likely not all will apply to your need to know, but we hope you do find some of particular interest.

• Recent articles related to prostate cancer 2021-01-10
• We thank Jim Barney & Keith Braganza of PCS Toronto for providing this information
• Prostate cancer regulator plays role in COVID-19, providing a promising treatment lead
  https://www.sciencedaily.com/releases/2020/12/201221134200.htm
• Delaying radiation therapy for prostate cancer unlikely to affect survival during coronavirus disease 2019
  https://acsjournals.onlinelibrary.wiley.com/doi/10.1002/cncr.33405
• Huge Prostate Cancer Genetics Study Highlights Disparities in Risk, Research
  https://www.ajmc.com/view/huge-prostate-cancer-genetics-study-highlights-disparities-in-risk-research
• How an Aggressive Form of Prostate Cancer Flips the Switch on Therapy
  https://www.genengnews.com/news/how-an-agressive-form-of-prostate-cancer-flips-the-switch-on-therapy/
• Diverse Prostate Cancer Study Identifies Plethora of New Risk Factors
  https://www.genengnews.com/news/diverse-prostate-cancer-study-identifies-plethora-of-new-risk-factors/
• Genes Help Explain Role of Race in Prostate Cancer Risk
  https://consumer.healthday.com/1-7-genes-may-help-explain-why-prostate-cancer-is-deadlier-in-black-men-2649730690.html
• Genetic Score Predicts Prostate Cancer Risk Across Ancestry Populations
  https://www.genomeweb.com/cancer/genetic-score-predicts-prostate-cancer-risk-across-ancestry-populations
• Negative MRI After Negative MRI Guided Biopsy Indicates Nil Risk OF Prostate Cancer: Study
  https://medicaldialogues.in/radiology/news/negative-mri-after-negative-mri-guided-biopsy-indicates-nil-risk-of-prostate-cancer-study-72892
• MRI frequently underestimates tumor size in prostate cancer
  https://www.sciencedaily.com/releases/2021/01/210107135655.htm
• The Latest Efforts in Precision Oncology for Advanced Prostate Cancer
  https://blog.dana-farber.org/insight/2020/12/the-latest-efforts-in-precision-oncology-for-advanced-prostate-cancer/
• New hope in fight against therapy-resistant prostate cancer
  https://www.sciencefocus.com/news/new-hope-in-fight-against-therapy-resistant-prostate-cancer/
• Prostate Cancer & Bone Health: What You Need to Know
  https://www.survivornet.com/articles/prostate-cancer-and-bone-health-what-you-need-to-know/
• Real-World Costs of First-Line Prostate Cancer Management Strategies
  https://www.journalofclinicalpathways.com/news/real-world-costs-first-line-prostate-cancer-management-strategies
• Treatment Options in Metastatic Castration-Resistant Prostate Cancer: A Year In Review
  https://www.urologytimes.com/view/treatment-options-in-metastatic-castration-resistant-prostate-cancer-a-year-in-review
• Men Undergoing Active Surveillance for Early Prostate Cancer See Lower Risk of Metastases, Death
  https://www.cancernetwork.com/view/men-undergoing-active-surveillance-for-early-prostate-cancer-see-lower-risk-of-metastases-death
• Geography Seen as Factor in Overtreatment of Low-Risk Prostate Cancer
  https://www.medpagetoday.com/hematologyoncology/prostatecancer/90428
• Inflammation from ADT may cause fatigue in prostate cancer patients
  https://www.sciencedaily.com/releases/2021/01/210104114113.htm
• Men’s experiences of radiotherapy treatment for localized prostate cancer and its long-term treatment side effects: a longitudinal qualitative study
  https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/127072-men-s-experiences-of-radiotherapy-treatment-for-localized-prostate-cancer-and-its-long-term-treatment-side-effects-a-longitudinal-qualitative-study.html
• New clues to prostate cancer: Why aggressive subtype can resist treatment
  https://medicalxpress.com/news/2021-01-clues-prostate-cancer-aggressive-subtype.html
• PSMA PET Imaging for Prostate Cancer Patient Education – Robert Flavell
  https://www.urotoday.com/video-lectures/imaging-prostate-cancer/video/1968-psma-pet-imaging-for-prostate-cancer-patient-education-robert-flavell.html
• A Veteran’s Call to Action: Take Charge, Know Your Risk for Prostate Cancer
  https://www.blogs.va.gov/VAntage/83057/veterans-call-action-take-charge-know-risk-prostate-cancer/
• Therapies for Clinically Localized Prostate Cancer: A Comparative Effectiveness Review
  https://pubmed.ncbi.nlm.nih.gov/33350857/
• New clues to prostate cancer
  https://www.eurekalert.org/pub_releases/2021-01/fu-nct010421.php
• Radiation after prostate cancer surgery may not be necessary
  https://www.news8000.com/i/radiation-after-prostate-cancer-surgery-may-not-be-necessary/
• Novel prostate cancer resistance mechanism could be a promising target
  https://www.drugtargetreview.com/news/79198/novel-prostate-cancer-resistance-mechanism-could-be-a-promising-target/
• The Impact of Altered Metabolism on the Regulation of IGF-II/H19 Imprinting Status in Prostate Cancer.
  https://assets.researchsquare.com/files/rs-135609/v1/c77883c6-b444-4ee3-97f5-c2d50229db73.pdf
• One Thing at a Time… Timeliness of Rehabilitation for Sexual Problems in Men With Prostate Cancer
  https://assets.researchsquare.com/files/rs-132005/v1/52f5c86e-bbf7-4ae6-8671-2a483240db56.pdf
• Drs. Oz and Roizen: Breakthrough in identifying prostate cancer
  https://www.telegraphherald.com/news/features/article_1229851e-7426-5408-8392-83670c724cf6.html
• Could a butterfly implant be the answer to prostate trouble? Metal device the size of a 10p coin works on swollen tissue
  https://www.dailymail.co.uk/health/article-9112951/Could-butterfly-implant-answer-prostate-trouble.html
• How race to track mystery gene with links to three cancers saved millions
  https://www.theguardian.com/society/2021/jan/10/how-race-to-track-mystery-gene-with-links-to-three-cancers-saved-millions
• Predicting low-risk prostate cancer
  https://www.health.harvard.edu/mens-health/predicting-low-risk-prostate-cancer
• Hormonal therapies for advanced prostate cancer linked to a higher risk of falls and fractures
  https://www.health.harvard.edu/blog/hormonal-therapies-for-advanced-prostate-cancer-linked-to-a-higher-risk-of-falls-and-fractures-2021010721738
• Early-onset metastatic and clinically advanced prostate cancer is a distinct clinical and molecular entity characterized by increased TMPRSS2-ERG fusions
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/early-onset-metastatic-and-clinically-advanced-prostate-cancer-is-a-distinct-clinical-and-molecular-entity-characterized-by-increased-tmprss2-erg-fusions/
• MAOA promotes prostate cancer cell perineural invasion through SEMA3C/PlexinA2/NRP1-cMET signaling
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/maoa-promotes-prostate-cancer-cell-perineural-invasion-through-sema3c-plexina2-nrp1-cmet-signaling/
• Loss and revival of androgen receptor signaling in advanced prostate cancer
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/loss-and-revival-of-androgen-receptor-signaling-in-advanced-prostate-cancer/
• QUANTIFICATION OF METASTATIC PROSTATE CANCER WHOLE-BODY TUMOR BURDEN WITH FDG PET PARAMETERS AND ASSOCIATIONS WITH OVERALL SURVIVAL AFTER FIRST LINE ABIRATERONE OR ENZALUTAMIDE: A SINGLE- CENTER RETROSPECTIVE COHORT STUDY
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/quantification-of-metastatic-prostate-cancer-whole-body-tumor-burden-with-fdg-pet-parameters-and-associations-with-overall-survival-after-first-line-abiraterone-or-enzalutamide-a-single-center-retro-2/
• Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/additional-snps-improve-risk-stratification-of-a-polygenic-hazard-score-for-prostate-cancer/
• Vimentin 3 Expression in Prostate Cancer Cells
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/vimentin-3-expression-in-prostate-cancer-cells/
• Urological outcomes in nonagenarians with prostate cancer
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/urological-outcomes-in-nonagenarians-with-prostate-cancer/
• Sexual function and rehabilitation after radiation therapy for prostate cancer: a review
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/sexual-function-and-rehabilitation-after-radiation-therapy-for-prostate-cancer-a-review/
• CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/chd1-loss-negatively-influences-metastasis-free-survival-in-r0-resected-prostate-cancer-patients-and-promotes-spontaneous-metastasis-in-vivo/
• Prostate cancer and sexual consequences among men who have sex with men
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/prostate-cancer-and-sexual-consequences-among-men-who-have-sex-with-men/
• Prostate Cancer Radiotherapy: Increased Biochemical Control and Late Toxicity in Men With Medication Allergies
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/prostate-cancer-radiotherapy-increased-biochemical-control-and-late-toxicity-in-men-with-medication-allergies/
• Long non-coding RNA AC245100.4 promotes prostate cancer tumorigenesis via the microRNA-145-5p/RBBP5 axis
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/long-non-coding-rna-ac245100-4-promotes-prostate-cancer-tumorigenesis-via-the-microrna-145-5p-rbbp5-axis/
• ADT-Related Inflammation May Cause Fatigue in Patients with Prostate Cancer
  https://www.docwirenews.com/docwire-pick/adt-related-inflammation-may-cause-fatigue-in-patients-with-prostate-cancer/
• Primary metastatic prostate cancer between prognosis or adequate/proper medical therapy
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/primary-metastatic-prostate-cancer-between-prognosis-or-adequate-proper-medical-therapy/
• Detecting recurrent prostate Cancer using multiparametric MRI, influence of PSA and Gleason grade
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/detecting-recurrent-prostate-cancer-using-multiparametric-mri-influence-of-psa-and-gleason-grade/
• Prostate cancer extracellular vesicles mediate intercellular communication with bone marrow cells and promote metastasis in a cholesterol-dependent manner
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/prostate-cancer-extracellular-vesicles-mediate-intercellular-communication-with-bone-marrow-cells-and-promote-metastasis-in-a-cholesterol-dependent-manner/
• A new compound targets the AF-1 of androgen receptor and decreases its activity and protein levels in prostate cancer cells
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/a-new-compound-targets-the-af-1-of-androgen-receptor-and-decreases-its-activity-and-protein-levels-in-prostate-cancer-cells/
• Role of MRI for the detection of prostate cancer
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/role-of-mri-for-the-detection-of-prostate-cancer/
• HDAC5 loss impairs RB repression of pro-oncogenic genes and confers CDK4/6 inhibitor resistance in cancer
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/hdac5-loss-impairs-rb-repression-of-pro-oncogenic-genes-and-confers-cdk4-6-inhibitor-resistance-in-cancer/
• Radiomic features for prostate cancer grade detection through formal verification
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/radiomic-features-for-prostate-cancer-grade-detection-through-formal-verification/
• Frequency of IL-10+CD19+ B cells in patients with prostate cancer compared to patients with benign prostatic hyperplasia
  https://www.docwirenews.com/condition-center/precision-medicine-in-prostate-cancer/precision-medicine-in-prostate-cancer-abstracts/frequency-of-il-10cd19-b-cells-in-patients-with-prostate-cancer-compared-to-patients-with-benign-prostatic-hyperplasia/
• Recent articles related to prostate cancer – DIET/EXERCISE 2021-01-10
• Mediterranean diet has the potential to effect progression of prostate cancer
  https://www.news-medical.net/news/20210107/Mediterranean-diet-has-the-potential-to-effect-progression-of-prostate-cancer.aspx
• Mediterranean diet named ‘Best Diet Overall’ of 2021: What is so special about this diet?
  https://www.thehealthsite.com/fitness/diet/mediterranean-diet-named-best-diet-overall-of-2021-what-is-so-special-about-this-diet-790354/
• Study Reveals: Men Should Eat Walnuts To Prevent Prostate Cancer
  https://www.brudirect.com/news.php?id=109644
• Ask the Doctors: Eat your carrots for potential help with prostate health
  https://syvnews.com/lifestyles/health-med-fit/ask-the-doctors-eat-your-carrots-for-potential-help-with-prostate-health/article_ef3dbf07-87fb-5c18-aa44-6808be86bff7.html
• What to know about vitamin E
  https://www.medicalnewstoday.com/articles/vitamin-e
• Assessing the Link Between Sugary Drinks and Cancer
  https://www.pharmacytimes.com/news/assessing-the-link-between-sugary-drinks-and-cancer
• A Plant-Based Diet Approach to Dealing with Prostate Cancer
  https://foodrevolution.org/blog/dealing-with-prostate-cancer-plant-based-diet/
• 20 Signs Your Diet Is Shortening Your Lifespan, According to Science
  https://www.eatthis.com/how-diet-shortens-lifespan/
• Foods That Help Prevent Cancer
  https://www.aarp.org/health/healthy-living/info-12-2012/foods-that-help-prevent-cancer.html#slide1
• Looking for Ways to Prevent Cancer? Learn How These 12 Superfoods Can Help Make A Difference
  https://www.onlymyhealth.com/twelve-superfoods-to-reduce-the-risk-of-cancer-1609953060
• Wellness at Every Age
  https://www.stuartmagazine.com/stuart-life/health-wellness/wellness-at-every-age/
• Title Changes in the Mineral Composition of Rat Femoral Bones Induced by Implantation of LNCaP Prostate Cancer Cells and Dietary Supplementation
  https://www.mdpi.com/2072-6643/13/1/100
• Increased oxidative stress and cancer biomarkers in the ventral prostate of older rats submitted to maternal malnutrition
  https://www.sciencedirect.com/science/article/abs/pii/S0303720720304500
• Circulating Vitamin D and Selenium Levels and Outcome in Prostate Cancer Patients: Lessons from the MARTINI-Lifestyle Cohort
  https://www.sciencedirect.com/science/article/abs/pii/S2405456920303072
• Feasibility and Acceptability of a Remotely Delivered, Web-Based Behavioral Intervention for Men With Prostate Cancer: Four-Arm Randomized Controlled Pilot Trial
  https://www.jmir.org/2020/12/e19238/

Movember Canada continues to be a significant source of funding for research into prostate cancer diagnosis & treatment, as well as raising awareness of this most common form of cancer among Canadian men. They also address other areas affecting men’s health including testicular cancer and mental health especially suicide prevention.

We are pleased to announce that through the donations of our many generous sponsors of our Movember Team we were able to raise $4,308 for this great cause in 2020.

Since 2011 when we first joined in supporting Movember the Durham Region sponsors of this important work, through our team campaigns, have raised over $26,000 for this cause. Thank you all very much.

With the major change to the structure of our support groups, as we learned in December 2019 that Prostate Cancer Canada (PCC) would no longer exist as a stand-alone entity, but would be absorbed into the Canadian Cancer Society (CCS), we were faced with several challenges. As these are resolved we will be communicating the results of those developments with you. PCC, through having established PCCN (the Prostate Cancer Canada Network) as a network of support groups across Canada, were able to provide quite an extensive array of educational materials, and other services to our groups.

One significant role PCC played was maintaining a register, on the internet, of the support groups across the country which allowed men and their caregivers to find local help in their experience with this, the most common form of cancer in Canadian men. This function, we want to tell you has been re-established through the www.ProstateCancerSupport.ca website which is still being built as more groups are added, now contains the majority of active support groups covering every Province in Canada.

We will add to this posting as new developments, which are receiving our concerted attention, allow. What we can assure you is that support in Durham Region continues to be available to those who need us.

We assure you that one on one peer support remains available by contacting us directly. Just go to Contact Us above.

However we are also posting news of on-line events that are available to our members from within our overall Prostate Cancer Support family – Simply go to Events on this site for information on these events from other groups.